By Charles A. Schiffer (auth.), Anjali S. Advani, Hillard M. Lazarus (eds.)
The present explosion of recent parts of controversy within the remedy of acute lymphocytic leukemia in adults and teenagers makes this accomplished e-book a miles wanted reference for hematologists and oncologists. This ebook assembles prime experts from around the world to hide the entire spectrum of ALL subtypes and their remedies. particular subject matters of dialogue contain symptoms for allogeneic bone marrow transplant in first entire remission, the function of minimum residual sickness in making therapy judgements, the therapy of teenagers, and the therapy of Philadelphia chromosome confident ALL with the appearance of the tyrosine kinase inhibitors. this can be the 1st booklet to concentration solely at the grownup ALL sufferer. It offers an entire evaluate of analysis, molecular pathogenesis, overview, and remedy for this crucial sufferer population.
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Additional resources for Adult Acute Lymphocytic Leukemia: Biology and Treatment
Et al. (2001). Facial diplegia as the presenting manifestation of acute lymphoblastic leukemia. The Mount Sinai Journal of Medicine, 68(6), 406–409. 2 Acute Lymphocytic Leukemia – Clinical Features and Making the Diagnosis 21 8. Mayo, G. , Carter, J. , & McKinnon, S. J. (2002). Bilateral optic disk edema and blindness as initial presentation of acute lymphocytic leukemia. American Journal of Ophthalmology, 134(1), 141–142. 9. Pui, C. H. (2006). Central nervous system disease in acute lymphoblastic leukemia: Prophylaxis and treatment.
Deregulated expression of the TAL1 gene by t(1;5)(p32;31) in patient with T-cell acute lymphoblastic leukemia. Genes, Chromosomes & Cancer, 23(1), 36–43. 52. , et al. (2002). A single split-signal FISH probe set allows detection of TAL1 translocations as well as SIL-TAL1 fusion genes in a single test. Leukemia, 16(4), 755–761. 53. Curry, J. , & Smith, M. T. (2003). Measurement of SIL-TAL1 fusion gene transcripts associated with human T-cell lymphocytic leukemia by real-time reverse transcriptase-PCR.
Clemmons, D. R. (1993). The insulin-like growth factors. Annual Review of Physiology, 55, 131–153. 39. , & LeRoith, D. (1996). The role of the insulin-like growth factor system in human cancer. Advances in Cancer Research, 68, 183–223. 40. , et al. (2003). Diagnostic cerebrospinal fluid examination in children with acute lymphoblastic leukemia: Significance of low leukocyte counts with blasts or traumatic lumbar puncture. Journal of Clinical Oncology, 21(2), 184–188. 41. Gilchrist, G. , et al.