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Extra resources for Atoms and the universe; an account of modern views of the structure of matter and the universe

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Mycological Investigations By far the most common fungus likely to be e n c o u n t e r e d in the oral cavity as a p a t h o g e n is C a n d i d a a l b i c a n s (Monilia a l b i c a n s ) . E x a m i n a t i o n for this o r g a n i s m is best carried out b y direct exam­ i n a t i o n of an u n s t a i n e d smear of a s c r a p i n g from the suspect area. U n d e r low p o w e r m a g n i f i c a t i o n the b r a n c h i n g m y c e l i a and b l a s t o s p o r e s are easily r e c o g n i s a b l e .

The p r e c i s e f u n c t i o n of the a u t o a n t i b o d i e s is not known. Laboratory Investigatioiis 31 C h e m i c a l E x a m i n a t i o n of the B l o o d B l o o d c h e m i s t r y d e t e r m i n a t i o n s are t a k e n to i n c l u d e the a n a l ­ y s i s of the n o n - p r o t e i n and i n o r g a n i c c o n s t i t u e n t s of the b l o o d . T h o s e n o r m a l l y c a l l e d for in o r a l d i a g n o s t i c p r o c e d u r e s are of calcium, p h o s p h o r u s and a l k a l i n e p h o s p h a t a s e E s t i m a t i o n s of this k i n d , u n t i l r e l a t i v e l y r e c e n t l y c a r r i e d out b y l a b o r i o u s c h e m i c a l and b i o c h e m i c a l t e c h n i q u e s , are n o w u n i v e r s a l l y c a r r i e d out in a u t o m a t i c e q u i p m e n t of a w i d e r a n g e of d e s i g n .

6) Immunofluorescence. T h i s is p e r h a p s the m o s t elegant m e t h o d of d e m o n s t r a t i n g a n t i b o d y f o r m a t i o n and f i x a t i o n onto tissue and is of great v a l u e in the study of a u t o i m m u n e m e c h ­ anisms. The p r i n c i p l e of this t e c h n i q u e d e p e n d s on the fact that a n t i b o d i e s combined w i t h f l u o r e s c e i n r e t a i n b o t h t h e i r i m m u n o ­ logical a c t i v i t y and the ability of the f l u o r e s c e i n to f l u o r e s c e under ultra violet light.

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